03:29

Day 27 - Happy Hormones: Leptin Resistance

by Samantha Linden, DBA, M.ED.

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This is Day 27 for a series of talks called “Happy Hormones: A 30-Day Gut Reset For Women”. If you have yet to start from Day 1, I suggest you do so to optimize your success and knowledge. A 30-day journey to improve brain clarity, gain more energy, prevent disease, and balance a healthy weight for women by balancing their hormones. Today, we discuss Leptin Resistance, which is known as a hormone that regulates appetite and energy levels. Disclaimer: Please remember that the suggested materials are only for educational and informational purposes. However, this does not replace professional medical advice, diagnosis, or treatment. If you have any concerns or questions about your health, please understand that you should always consult a physician or other healthcare professional.

HormonesEnergyWeight ManagementBrain ClarityDisease PreventionEducationEftPerfectionismMind Body ConnectionChronic PainBody ScanTraditional MedicineEmotional HealthSelf CompassionSelf AcceptanceStressEft TappingBody Scan ExerciseTraditional Chinese MedicineEmotional Root Of Physical SymptomsWomen Health

Transcript

Welcome back.

My name is Samantha Linden,

Also known as the Blissful Soul.

This is our series,

Happy Hormones,

A 30-day gut reset for women.

If you haven't started from day one yet,

I highly recommend doing so to maximize your success and understanding.

Today we are going to discuss leptin resistance.

When your brain becomes used to high levels of leptin,

A hormone that controls appetite and energy,

You develop leptin resistance.

This means your brain doesn't recognize when you're full,

Even if you store plenty of fat.

As a result,

When you eat more,

You gain weight.

Leptin resistance happens when your brain mistakes your body as having low energy stores.

This triggers it to slow your metabolism and make you eat more to build up fat.

This cycle can keep individuals overweight or obese.

Several factors can contribute to leptin resistance,

Including chronic inflammation,

High leptin levels,

Elevated fat metabolites,

Problems transporting leptin across the brain barrier.

Obesity can trigger leptin resistance,

Which in turn worsens obesity.

Factors like chronic stress,

Inflammation,

Psychological stress,

And gut microbiome imbalances can also contribute to the problem.

There are other consequences of leptin resistance.

As mentioned,

Leptin resistance affects how your body signals fullness.

This leads to increased appetite,

Overeating,

And storing calories as fat instead of using them for energy.

Weight loss becomes harder,

And maintaining a healthy weight is challenging in the long term.

High leptin levels and leptin resistance can also make you tired and increase your body's reactivity to histamine,

Leading to allergic reactions and histamine intolerance.

So how might you manage leptin resistance?

To improve leptin resistance,

Aim to do the following,

As they can have a significant impact in the long term.

Maintain a healthy weight,

Exercise regularly,

Get regular sleep,

Manage stress.

These lifestyle changes can improve metabolism,

Control appetite,

Reduce body fat,

And enhance overall health.

Fasting can also help improve leptin sensitivity.

Eating late in the day,

Especially after 8 p.

M.

,

Has been linked to higher leptin resistance,

Increased hunger,

And more weight gain.

Some studies suggest fasting can reduce inflammation and reset leptin receptors,

Promoting weight loss.

So try to follow fasting schedules that complement your hormones,

And when possible,

Take your last bite before 8 p.

M.

As we are coming close to your next cycle,

Think about planning your next one when your first day starts.

Tomorrow,

We will discuss how fasting might affect brain-derived neurotrophic factors,

BDNF.

See you soon.

Meet your Teacher

Samantha Linden, DBA, M.ED.Boston, MA, USA

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© 2026 Samantha Linden, DBA, M.ED.. All rights reserved. All copyright in this work remains with the original creator. No part of this material may be reproduced, distributed, or transmitted in any form or by any means, without the prior written permission of the copyright owner.

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